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KMID : 0352519920290030591
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Korea Univercity Medical Journal
1992 Volume.29 No. 3 p.591 ~ p.603
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An Experimental Study of Repair of the Articular Cartilage Following the Injury of Articular Cartilage in Rabbits
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Lee Hong-Keun
Park Sang-Won
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Abstract
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In the current state of increasing incidence on total joint replacement arthroplasty in the treatment of human osteoarthritis, it is still important to prevent osteoarthritis, with a particualr emphasis on the possibility of stimulating the healing and regeneration of damaged articular cartilage. Recent advances in arthroscopic surgery have provided a less aggressive surgical operation, including subchondral abrasion arthroplasty in osteoarthritis or osteochondral defect. However. it seems that arthroscopic debridement alone is not enough to stimulate the healing of articular cartilage defect. Although various methods for stimulating repair of articular cartilage defect have been tried, no successful method has been found.
The purpose of this experimental study is to investigate the effect of multiple drillings on the surgically induced full thickeness defect to the subchondral bone plate, and to compare it with the reparative process of the superficial injury and the full thickness injury of articular cartilage in the rabbits.
Forty-five Korean domestic rabbits were divided into three groups :
Group I was superficially Injured by four cuts on the articular cartilage of the medial femoral condyle within 3mm in diameter of round shape with No.11 blade : Group Ⅱ had the full thickness defect of round shape of 3mm in diameter to the subchondral bone of articular cartilage of medial femoral condyle ; Group Ⅲ had the four drillings of 5mm in depth into the medullary cavity with Kirschner wire of 1mm in diameter after the full thickness defect of round shape of 3mm in diameter was created to subchondral bone of the articular cartilage of medial femoral condyle.
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